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LIH383 (TFA)

CAT: 0804-HY-P10333A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10333A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LIH383 TFA is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM) . LIH383 TFA efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling[1].
UNSPSC
12352209
Target
CXCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Purity
99.83
Smiles
O=C(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=CC=C2)N.O=C(O)C(F)(F)F.[x]
Molecular Formula
C45H72N16O8S.xC2HF3O2
Molecular Weight
997.22 (free base)
References & Citations
[1]Meyrath M, et al. The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nat Commun. 2020 Jun 19;11 (1) :3033.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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