MPSD (TFA)

• Description:

  MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD (HY-P10471) . MPSD TFA is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS) . MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition[1].

• Product Name Alternative:

  MARCKS-ED (TFA)

• UNSPSC:

  12352209

• Target:

  MARCKS; PKC

• Type:

  Peptides

• Related Pathways:

  Cytoskeleton; Epigenetics; TGF-beta/Smad

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/mpsd-tfa.html

• Purity:

  99.81

• Solubility:

  DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

• Smiles:

  O=C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CO)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.OC(C(F)(F)F)=O.[x]

• Molecular Formula:

  C147H243N41O31.xC2HF3O2

• Molecular Weight:

  3080.76 (free base)

• References & Citations:

  [1]Morton LA, et al., MARCKS-ED peptide as a curvature and lipid sensor. ACS Chem Biol. 2013 Jan 18;8 (1) :218-25.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported