Products for Research Use Only

HAChE-IN-8

CAT: 0013-GTR19262413-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262413-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HAChE-IN-8 (Compound S-12) is an orally active and selective inhibitor of hAChE, with an IC50 of 0.486 μM. It also inhibits BACE-1 with an IC50 of 0.542 μM, but shows negligible inhibition of Dyrk1A (IC50>10 μM) . This compound reduces Aβ aggregation, exhibits good blood-brain barrier penetration, and is primarily used in Alzheimer's disease research.
Field of Research
Cell Biology, Neuroscience, Signal Transduction
Molecular Formula
C25H22N4O4
Storage Conditions
-20°C
Notes
For research use only.