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NK7-902

CAT: 0013-GTR19258780-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258780-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NK7-902 is a CRBN molecular glue degrader of NEK7. It fully degrades NEK7 in human primary monocytes and whole blood, yet only partially inhibits NLRP3-dependent IL-1β production. NK7-902 results in profound and lasting degradation of NEK7, but only temporarily blocks NLRP3 inflammasome activation in non-human primates via oral administration. The compound demonstrates activity in mouse systems.
Field of Research
Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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