Products for Research Use Only

BJP-07-017-3

CAT: 0013-GTR19250156-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250156-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BJP-07-017-3 is a potent, covalent Pin1 inhibitor with an IC50 of 9 nM. It selectively targets Cys113, triggering Pin1 unfolding and subsequent proteasomal degradation. This compound is a valuable chemical probe for studying Pin1 function in cancer and neurodegenerative disease models both in vitro and in vivo.
CAS Number
2468783-22-2
Smiles
C ([C@H] (NC (=O) [C@H]1N (C ([C@H] (CC2=CC=CC=C2) N (C (CCl) =O) C) =O) CCCC1) C (N[C@@H] (CCCNC (N) =O) C (N) =O) =O) C=3C=4C (NC3) =CC=CC4
Molecular Formula
C35H45ClN8O6
Molecular Weight
709.235
Storage Conditions
-20°C
Notes
For research use only.