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CGAS-IN-4

CAT: 0013-GTR19250055-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250055-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGAS-IN-4 (Compound 36) is a potent, orally bioavailable inhibitor of the cGAS enzyme, demonstrating nanomolar IC50 values against both human and mouse targets. It effectively reduces cGAMP production in THP-1 cells and has shown anti-inflammatory activity in an in vivo model of Concanavalin A-induced acute liver injury, supporting research in innate immunity and inflammatory diseases.
CAS Number
2987886-49-5
Field of Research
Immunology & Inflammation, Infectious Disease & Virology
Smiles
C[C@H]1C=2C=3C (NC2CCN1C (=O) C=4N=CC (OCCO) =CN4) =C (Cl) C (Cl) =CC3
Molecular Formula
C19H18Cl2N4O3
Molecular Weight
421.277
Storage Conditions
-20°C
Notes
For research use only.

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