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CGAS-IN-2

CAT: 0804-HY-160546-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160546-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC50 of 0.01512 μM for h-cGAS[1].
CAS Number
2765273-11-6
UNSPSC
12352005
Target
Cyclic GMP-AMP Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cgas-in-2.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H]1C(C2=CC=C3Cl)=C(C[C@H](N1C(COC)=O)C)NC2=C3Cl
Molecular Formula
C16H18Cl2N2O2
Molecular Weight
341.23
References & Citations
[1]Ventus Therapeutics U.S., Inc. Pyrido[4,3-b]indole derivatives and their use as pharmaceuticals. World Intellectual Property Organization, WO2022066851 A1 2022-03-31
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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