ARN-6039

• Description:

  ARN-6039 is an orally available inverse agonist of RORγ for autoimmune demyelinating disease.

• Product Name Alternative:

  PF 00477736

• UNSPSC:

  12352005

• Target:

  ROR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/arn-6039.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C (C=C (C2=C1) CC (C2=O) CC3=NC=CC=C3C (F) (F) F) N4CCOCC4

• Molecular Formula:

  C21H21F3N2O3

• Molecular Weight:

  406.40

• References & Citations:

  [1]Vankayalapati, Hariprasad; Yerramreddy, Venkatakrishnareddy. Preparation of dihydroindenone derivatives for use as retinoic acid-related orphan nuclear receptor modulators. US20150072980A1

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  1675206-11-7