ARN-6039

• Description :

  ARN-6039 is an orally available inverse agonist of RORγ for autoimmune demyelinating disease.

• Product Name Alternative :

  PF 00477736

• UNSPSC :

  12352005

• Target :

  ROR

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/arn-6039.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(C=C(C2=C1)CC(C2=O)CC3=NC=CC=C3C(F)(F)F)N4CCOCC4

• Molecular Formula :

  C21H21F3N2O3

• Molecular Weight :

  406.40

• References & Citations :

  [1]Vankayalapati, Hariprasad; Yerramreddy, Venkatakrishnareddy. Preparation of dihydroindenone derivatives for use as retinoic acid-related orphan nuclear receptor modulators. US20150072980A1

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [1675206-11-7]