ARN-6039

CAT: 0931-T25109-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T25109-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1675206-11-7

Target

Others, ROR

Related Pathways

Metabolism, Others

Bioactivity

ARN-6039, an orally available inverse agonist of RORγ, targets Autoimmune Neuroinflammatory Demyelinating Disease. Its efficacy was demonstrated in a RORγ-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM) .

Smiles

COc1cc2C(=O)C(Cc3ncccc3C(F)(F)F)Cc2cc1N1CCOCC1

Molecular Formula

C21H21F3N2O3

Molecular Weight

406.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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