ARN-6039

• Target :

  Others|||ROR

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  ARN-6039, an orally available inverse agonist of ROR?, targets Autoimmune Neuroinflammatory Demyelinating Disease. Its efficacy was demonstrated in a ROR?-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM) .

• Smiles :

  COc1cc2C(=O)C(Cc3ncccc3C(F)(F)F)Cc2cc1N1CCOCC1

• Molecular Formula :

  C21H21F3N2O3

• Molecular Weight :

  406.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1675206-11-7