ARN-6039

CAT: 0931-T25109-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T25109-01Size:25 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1675206-11-7
Target
Others|||ROR
Related Pathways
Metabolism|||Others
Bioactivity
ARN-6039, an orally available inverse agonist of ROR?, targets Autoimmune Neuroinflammatory Demyelinating Disease. Its efficacy was demonstrated in a ROR?-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM) .
Smiles
COc1cc2C(=O)C(Cc3ncccc3C(F)(F)F)Cc2cc1N1CCOCC1
Molecular Formula
C21H21F3N2O3
Molecular Weight
406.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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