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DA-143

CAT: 0013-GTR19238585-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238585-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DA-143 is a potent and selective DNA-PKcs inhibitor (IC50: 2.5 nM) with significantly weaker activity against mTOR, PI3KΔ, and ATM. It blocks DNA-PKcs substrate phosphorylation and, in research settings, has been shown to sensitize cancer cells to chemotherapeutic agents like doxorubicin in vitro.
Field of Research
Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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