DA-023

• Description :

  DA-023 (Compound 4) is a selective positive allosteric modulator (PAM) of EAAT2 with an EC50 value of 1 nM[1].

• UNSPSC :

  12352005

• Target :

  EAAT

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/da-023.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN1CCN(C(C2=NN=NN2CCC3=CC=CC=C3)C4=CC=CN=C4)CC1

• Molecular Formula :

  C20H25N7

• Molecular Weight :

  363.46

• References & Citations :

  [1]Fontana ACK, et al. Synthesis and Structure-Activity Relationships for Glutamate Transporter Allosteric Modulators. J Med Chem. 2024;67 (8) :6119-6143.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2585643-97-4]