DA-023

CAT: 0804-HY-162454Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162454Size:1 Each
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Description
DA-023 (Compound 4) is a selective positive allosteric modulator (PAM) of EAAT2 with an EC50 value of 1 nM[1].
CAS Number
[2585643-97-4]
UNSPSC
12352005
Target
EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/da-023.html
Solubility
10 mM in DMSO
Smiles
CN1CCN(C(C2=NN=NN2CCC3=CC=CC=C3)C4=CC=CN=C4)CC1
Molecular Formula
C20H25N7
Molecular Weight
363.46
References & Citations
[1]Fontana ACK, et al. Synthesis and Structure-Activity Relationships for Glutamate Transporter Allosteric Modulators. J Med Chem. 2024;67 (8) :6119-6143.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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