Products for Research Use Only
RegisterLogin

GPS1573

CAT: 0013-GTR19238470-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19238470-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GPS1573 is a potent and selective non-competitive antagonist of the melanocortin 2 receptor (MC2R), inhibiting ACTH-stimulated signaling with an IC50 of 66 nM. Its high selectivity makes it a valuable research tool for studying MC2R function in models of Cushing's disease and adrenal disorders, applicable in both in vitro and in vivo experimental systems.
CAS Number
2445822-54-6
Smiles
C ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (CCCNC (=N) N) C (N) =O) =O) CCCNC (=N) N) =O) CCCCN) =O) CCCCN) =O) =O) C (C) C) =O) C) =O) CCCCN) =O) =O) NC ([C@@H] (NC ([C@H] (NC (=O) [C@H]2N (C ([C@H] (CCCC) N) =O) CCC2) CC3=CC=CC=C3) =O) CCCNC (=N) N) =O) C=4C=5C (NC4) =CC=CC5
Molecular Formula
C86H138N28O14
Molecular Weight
1788.19
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

H-Nle-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Ala-Val-Gly-Lys-Lys-Arg-Arg-NH2
CAS Number2445822-54-6
PubChem CID172419333
IUPAC Name(2S)-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carboxamide
Molecular FormulaC86H138N28O14
Molecular Weight1788.2
XLogP-1
Topological Polar Surface Area718
Hydrogen Bond Donor Count27
Hydrogen Bond Acceptor Count21
Rotatable Bond Count63
Heavy Atom Count128
Formal Charge0
Complexity3570
SMILES
CCCC[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N)N
InChI
InChI=1S/C86H138N28O14/c1-5-6-30-57(90)83(128)114-45-24-38-68(114)81(126)112-66(47-54-27-11-8-12-28-54)79(124)109-64(37-23-44-100-86(96)97)77(122)111-67(48-55-49-101-58-31-14-13-29-56(55)58)80(125)110-65(46-53-25-9-7-10-26-53)78(123)108-61(33-16-19-40-88)73(118)103-52(4)72(117)113-70(51(2)3)82(127)102-50-69(115)104-60(32-15-18-39-87)74(119)106-62(34-17-20-41-89)76(121)107-63(36-22-43-99-85(94)95)75(120)105-59(71(91)116)35-21-42-98-84(92)93/h7-14,25-29,31,49,51-52,57,59-68,70,101H,5-6,15-24,30,32-48,50,87-90H2,1-4H3,(H2,91,116)(H,102,127)(H,103,118)(H,104,115)(H,105,120)(H,106,119)(H,107,121)(H,108,123)(H,109,124)(H,110,125)(H,111,122)(H,112,126)(H,113,117)(H4,92,93,98)(H4,94,95,99)(H4,96,97,100)/t52-,57-,59-,60-,61-,62-,63-,64-,65-,66+,67+,68-,70-/m0/s1
InChIKey
PXMZZYSWAXSIMV-XWOIBVINSA-N
Chemical Structure
2D Structure
2D structure of H-Nle-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Ala-Val-Gly-Lys-Lys-Arg-Arg-NH2
CAS: 2445822-54-6
CID: 172419333
Formula: C86H138N28O14
MW: 1788.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1788.2
XLogP3-1
Hydrogen Bond Donor Count27
Hydrogen Bond Acceptor Count21
Rotatable Bond Count63
Exact Mass1787.09473119
Monoisotopic Mass1787.09473119
Topological Polar Surface Area718 Ų
Heavy Atom Count128
Formal Charge0
Complexity3570
Isotope Atom Count0
Defined Atom Stereocenter Count13
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19264785-01GPS167
GTR19213214GPS167

Alternative Products

CatalogName
HY-P10571-01GPS1573
350595GPS1573 Peptide
CRB1000575-01GPS1573 - (Hormones)

Popular Products