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GPS1573

CAT: 0931-T88880-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88880-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2445822-54-6
Bioactivity
GPS1573 is a non-competitive antagonist of the melanocortin 2 receptor (MC2R) that blocks the ACTH-stimulated activity of MC2R in a dose-dependent manner (IC50=66 nM) . Due to its high selectivity in antagonizing MC2R, GPS1573 is utilized for research in Cushings disease.
Smiles
C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)C)=O)CCCCN)=O)=O)NC([C@@H](NC([C@H](NC(=O)[C@H]2N(C([C@H](CCCC)N)=O)CCC2)CC3=CC=CC=C3)=O)CCCNC(=N)N)=O)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C86H138N28O14
Molecular Weight
1788.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C