Products for Research Use Only

PROTAC PARP1 degrader-2

CAT: 0013-GTR19237754-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237754-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACPARP1 degrader-2 (Compound 72) is a potent and cell-permeable PARP-targeting PROTAC, demonstrating a DC50 below 10 nM in MDA-MB-231 cells and inhibiting viability in MDA-MB-436 cells with an IC50 under 100 nM. It serves as a valuable chemical tool for investigating PARP biology and targeted protein degradation in cancer research models, both in vitro and in vivo.
CAS Number
2923686-62-6
Field of Research
Cell Biology
Smiles
O=C (NC1CCN (C2=CC=C3C (=O) N (C (=O) C3=C2) C4C (=O) NC (=O) CC4) CC1) C5=NC (F) =C (C=C5) N6CCN (CC=7C=CC=8N=C (C (=O) NC8C7F) C) CC6
Molecular Formula
C38H37F2N9O6
Molecular Weight
753.75
Storage Conditions
-20°C
Notes
For research use only.