Products for Research Use Only
RegisterLogin

COB-187

CAT: 0013-GTR19236780-02Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19236780-02Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
COB-187 is a potent, selective, and ATP-competitive GSK-3β inhibitor that acts via reversible engagement of Cys-199. This small molecule has demonstrated utility in cellular research, suppressing LPS-induced cytokine and SARS-CoV-2 spike protein-triggered CXCL10 production in vitro.
CAS Number
1862177-86-3
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
S=C1SCC (O) (C=2C=CC=CC2) N1CC=3C=CN=CC3
Molecular Formula
C15H14N2OS2
Molecular Weight
302.41
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-Hydroxy-4-phenyl-3-(pyridin-4-ylmethyl)-1,3-thiazolidine-2-thione
CAS Number1862177-86-3
PubChem CID118668000
IUPAC Name4-hydroxy-4-phenyl-3-(pyridin-4-ylmethyl)-1,3-thiazolidine-2-thione
Molecular FormulaC15H14N2OS2
Molecular Weight302.4
XLogP2.2
Topological Polar Surface Area93.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity354
SMILES
C1C(N(C(=S)S1)CC2=CC=NC=C2)(C3=CC=CC=C3)O
InChI
InChI=1S/C15H14N2OS2/c18-15(13-4-2-1-3-5-13)11-20-14(19)17(15)10-12-6-8-16-9-7-12/h1-9,18H,10-11H2
InChIKey
RPAZLTQZYXMTQP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-Hydroxy-4-phenyl-3-(pyridin-4-ylmethyl)-1,3-thiazolidine-2-thione
CAS: 1862177-86-3
CID: 118668000
Formula: C15H14N2OS2
MW: 302.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight302.4
XLogP32.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass302.05475542
Monoisotopic Mass302.05475542
Topological Polar Surface Area93.8 Ų
Heavy Atom Count20
Formal Charge0
Complexity354
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR18008269COB Antibody
GTR18008206COB Antibody
GTR17949980COB Antibody
GTR18008267Cob Antibody
GTR18008470Cob Antibody
GTR19210381-01NMI-187
GTR19196372-01Tak 187
GTR19239239-01PMMB-187
GTR18894215AC 187
GTR19273930-01EGFR-IN-187

Alternative Products

CatalogName
HY-162675-01COB-187
PHY1116ACOB Antibody
MBS7011950-01Recombinant Cytochrome b (cob)
E010909Human COB ELISA Kit
OKCD04283-96WCOB ELISA Kit (Human)
T200126-01PMMB-187
B5424-.5AC 187
T69636-01NMI-187
CRB1000584-01BIM 187
HY-117850TAK 187

Popular Products