Products for Research Use Only

YM-344031

CAT: 0013-GTR19233888-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19233888-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YM-344031 is a potent and orally bioavailable CCR3 antagonist, inhibiting eotaxin-1 and RANTES binding with IC50 values of 3.0 and 16.3 nM, respectively. It blocks CCR3-mediated calcium flux, chemotaxis, and eosinophil shape change in vitro, and has demonstrated efficacy in preventing allergic skin reactions in murine models.
CAS Number
671204-98-1
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
C (C1=CC2=C (C=C1) C=C (F) C=C2) N3C[C@H] (NC (C=C4CCN (C (=O) C5=C (C) C=CC=N5=O) CC4) =O) CC3
Molecular Formula
C29H31FN4O3
Molecular Weight
502.58
Storage Conditions
-20°C
Notes
For research use only.

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