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YM-90709

CAT: 0013-GTR19171422-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171422-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YM-90709 is a novel small molecule antagonist that selectively blocks the interleukin-5 (IL-5) and IL-5 receptor interaction. It is a valuable research tool for studying eosinophil biology and has demonstrated utility in both in vitro assays and in vivo models of allergic asthma and other eosinophilic diseases.
CAS Number
163769-88-8
Product Name Alternative
JAK2, inhibit, ILReceptor, IL-5, IL-5R, Inhibitor, Interleukin Related, Interleukin, IL Receptor, eosinophils, GM-CSF, YM90709, YM-90709, YM 90709
Field of Research
Immunology & Inflammation
Purity
99.67% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.56 mM) ; DMSO:18 mg/mL (50.08 mM)
Smiles
COc1cc2CC (C) (C) n3c (cc4nc5ccccc5nc34) -c2cc1OC
Molecular Formula
C22H21N3O2
Molecular Weight
359.42
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

YM 90709

LSM-2128 is a quinoxaline derivative.

CAS Number163769-88-8
PubChem CID1103147
IUPAC Name16,17-dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2,4,6,8,10,12,14,16,18-nonaene
Molecular FormulaC22H21N3O2
Molecular Weight359.4
XLogP3.6
Topological Polar Surface Area49.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count27
Formal Charge0
Complexity556
SMILES
CC1(CC2=CC(=C(C=C2C3=CC4=NC5=CC=CC=C5N=C4N31)OC)OC)C
InChI
InChI=1S/C22H21N3O2/c1-22(2)12-13-9-19(26-3)20(27-4)10-14(13)18-11-17-21(25(18)22)24-16-8-6-5-7-15(16)23-17/h5-11H,12H2,1-4H3
InChIKey
HIXSPVQXXDULHS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of YM 90709
CAS: 163769-88-8
CID: 1103147
Formula: C22H21N3O2
MW: 359.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight359.4
XLogP33.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass359.16337692
Monoisotopic Mass359.16337692
Topological Polar Surface Area49.2 Ų
Heavy Atom Count27
Formal Charge0
Complexity556
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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B1074-50YM-90709
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