Products for Research Use Only

BWA-6047

CAT: 0013-GTR19258028-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258028-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM) . It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C42H46ClN5O7
Storage Conditions
-20°C
Notes
For research use only.