Products for Research Use Only

PROTAC TG2 degrader-1

CAT: 0013-GTR19230493-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230493-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC TG2 Degrader-1 (Compound 11) is a VHL-recruiting PROTAC molecule that binds tissue transglutaminase (TG2) with a K D of 68.9 μM. It induces proteasomal degradation of TG2, reducing its levels in ovarian cancer cells in vitro, making it a useful tool for studying TG2 biology and targeted protein degradation.
Field of Research
Pharmacology & Drug Discovery, Protein Biochemistry
Molecular Formula
C55H73N9O10S
Molecular Weight
1052.29
Storage Conditions
-20°C
Notes
For research use only.