Products for Research Use Only

OATD-02

CAT: 0013-GTR19231446-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231446-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OATD-02 is a potent, orally bioavailable dual inhibitor of Arginase 1 and 2 with slow dissociation kinetics, showing low nanomolar IC50 values across human, mouse, and rat enzymes. It reverses arginase-mediated immunosuppression in the tumor microenvironment and is a valuable tool for immuno-oncology research, particularly in melanoma models, as demonstrated in both in vitro and in vivo studies.
CAS Number
2146132-73-0
Field of Research
Immunology & Inflammation
Smiles
C (O) (=O) [C@]1 (N) [C@H] (CN (C) C) CC[C@@H] (CCB (O) O) C1
Molecular Formula
C12H25BN2O4
Molecular Weight
272.15
Storage Conditions
-20°C
Notes
For research use only.