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OATD-02 hydrochloride

CAT: 0931-T89315-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89315-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Arginase
Related Pathways
Immunology/Inflammation
Bioactivity
OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. It is an orally effective, competitive, reversible, and non-covalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride serves as a sustained-release inhibitor that efficiently blocks the activity of intracellular arginases, with IC50 values of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1) . It effectively eliminates tumor-induced immunosuppression caused by both types of arginases. This compound is utilized in research studies on melanoma.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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