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IITZ-02

CAT: 0013-GTR19273169-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273169-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IITZ-02 is a lysosomotropic autophagy inhibitor. It enhances autophagosome accumulation but inhibits autophagosome degradation by impairing lysosomal function, ultimately leading to autophagy suppression. IITZ-02 disrupts mitochondrial membrane potential and induces apoptosis through a mitochondria-mediated pathway. It shows potent anti-tumor activity in MDA-MB-231 xenograft mouse models and is applicable in cancer research.
CAS Number
1807988-46-0
Smiles
N=1C (=NC (=NC1NC=2C=CC (=CC2) C3=NC=4C=CC=CC4N3) N5CCOCC5) NC6=CC=C (OC) C=C6
Molecular Formula
C27H26N8O2
Molecular Weight
494.56
Storage Conditions
-20°C
Notes
For research use only.

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