NF-κB-IN-11

CAT: 0013-GTR19218974-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19218974-01Size:25 mg

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Description

NF-κB-IN-11 is a potent small molecule inhibitor that suppresses TNF-α-induced NF-κB activation and nuclear translocation by reducing phospho-IKK, IκBα, and p65 levels. It demonstrates anti-inflammatory efficacy in a DSS-induced mouse colitis model and shows a high oral MTD (>1852 mg/kg), supporting its use in inflammatory disease research.

CAS Number

2768833-35-6

Field of Research

Signal Transduction

Smiles

C (OC) (=O) C=1C2C (C#CC3=CC=C (C) C=C3) CC (O2) C1C (OC) =O

Molecular Formula

C19H18O5

Molecular Weight

326.34

Storage Conditions

-20°C

Notes

For research use only.

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NF-κB-IN-11

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