Products for Research Use Only

ALK/EGFR-IN-2

CAT: 0013-GTR19218698-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218698-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ALK/EGFR-IN-2 is a potent dual ALK and EGFR inhibitor that induces apoptosis and G0/G1 cell cycle arrest. It demonstrates strong anti-proliferative activity in vitro against H1975, PC9, and BaF3-EML4-ALK cell lines with nanomolar IC50 values. This compound is a valuable research tool for studying oncogenic kinase signaling and resistance mechanisms in non-small cell lung cancer models.
CAS Number
2730432-75-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (CCN (C) C) (C) C1=C (NC (C=C) =O) C=C (NC=2N=C (NC3=C (S (CC) =O) C=CC=C3) C (Cl) =CN2) C (OC) =C1
Molecular Formula
C27H34ClN7O3S
Molecular Weight
572.12
Storage Conditions
-20°C
Notes
For research use only.