PKM2 activator 7

PKM2 activator 7

• UNSPSC Description: PKM2 activator 7 (Compd B4) is a PKM2 activator with the AC50 of 0.144 μM. PKM2 activator 7 suppresses DSS (HY-116282C)-induced colitis by inhibiting T cell growth in mouse colitis model[1].
• Target Antigen: Pyruvate Kinase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pkm2-activator-7.html
• Smiles: C=C([C@H]1[C@H](O2)[C@H]3[C@@](O3)(C)CC/C=C(COC(F)(F)F)\CC1)C2=O
• Molecular Weight: 332.31
• References & Citations: [1]Ma L, et al. Design, synthesis, and biological evaluation of novel sesquiterpene lactone derivatives as PKM2 activators with potent anti-ulcerative colitis activities. Eur J Med Chem. 2024;272:116426.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported