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ARN-6039

CAT: 0013-GTR19199482-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19199482-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ARN-6039 is an orally bioavailable RORγ inverse agonist developed for autoimmune neuroinflammatory demyelinating disease research. It inhibits RORγ activity, demonstrated by an IC50 of 360 nM in a cellular reporter assay and 220 nM in suppressing IL-17 release from primary CD4+ T cells. This tool compound is used in vitro and in vivo to study Th17 cell biology and autoimmune disease mechanisms.
CAS Number
1675206-11-7
Field of Research
Metabolism Research
Smiles
COc1cc2C (=O) C (Cc3ncccc3C (F) (F) F) Cc2cc1N1CCOCC1
Molecular Formula
C21H21F3N2O3
Molecular Weight
406.40
Storage Conditions
-20°C
Notes
For research use only.

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