Products for Research Use Only
RegisterLogin

SK-216

CAT: 0013-GTR19196485-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19196485-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SK-216 is a specific PAI-1 inhibitor that suppresses tumor angiogenesis by blocking VEGF-induced HUVEC migration and tube formation in vitro. It has also demonstrated efficacy in an in vivo model, alleviating bleomycin-induced pulmonary fibrosis in mice, highlighting its research applications in oncology and fibrotic disease.
CAS Number
654080-03-2
Product Name Alternative
SK216, SK-216, SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor, SK 216
Field of Research
Metabolism Research
Purity
98.29% (May vary between batches)
Solubility
H2O:5.38 mg/mL (10.08 mM)
Smiles
O=C ([O-]) C (C ([O-]) =O) CCCCCOC1=CC2=CC=C (C=C2C=C1) C3=NC4=CC (C (C) (C) C) =CC=C4O3.[Na+].[Na+]
Molecular Formula
C29H29NNa2O6
Molecular Weight
533.52
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

CID 52916994
CAS Number654080-03-2
PubChem CID52916994
IUPAC Namedisodium;2-[5-[6-(5-tert-butyl-1,3-benzoxazol-2-yl)naphthalen-2-yl]oxypentyl]propanedioate
Molecular FormulaC29H29NNa2O6
Molecular Weight533.5
Topological Polar Surface Area116
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Heavy Atom Count38
Formal Charge0
Complexity726
SMILES
CC(C)(C)C1=CC2=C(C=C1)OC(=N2)C3=CC4=C(C=C3)C=C(C=C4)OCCCCCC(C(=O)[O-])C(=O)[O-].[Na+].[Na+]
InChI
InChI=1S/C29H31NO6.2Na/c1-29(2,3)21-11-13-25-24(17-21)30-26(36-25)20-9-8-19-16-22(12-10-18(19)15-20)35-14-6-4-5-7-23(27(31)32)28(33)34;;/h8-13,15-17,23H,4-7,14H2,1-3H3,(H,31,32)(H,33,34);;/q;2*+1/p-2
InChIKey
YYTGMMYYLGKWIK-UHFFFAOYSA-L
Chemical Structure
2D Structure
2D structure of CID 52916994
CAS: 654080-03-2
CID: 52916994
Formula: C29H29NNa2O6
MW: 533.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight533.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass533.17902621
Monoisotopic Mass533.17902621
Topological Polar Surface Area116 Ų
Heavy Atom Count38
Formal Charge0
Complexity726
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19211600-01NB-216
GTR19187707-01SB-216
GTR19236405-01LW-216
GTR19258650-01MTX-216
GTR19233995-01Anticancer agent 216
GTR19276532-01CRBN ligand-216
GTR19262660-01Antibacterial agent 216
GTR19210419-01SK-575
GTR17969902SK Antibody
GTR19209704-01SK 946

Alternative Products

CatalogName
HY-122714-01SK-216
6187/50SK 216 50 mg
6187/10SK 216 10 mg
T206251-01MTX-216
HY-163724LW-216
456357-01ML-216
T60757-01SB-216
MBS5810842NB-216

Popular Products