WT-161 (Standard)

CAT: 0804-HY-100871RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100871RSize:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WT-161 (Standard) is the analytical standard of WT-161 (HY-100871) . This product is intended for research and analytical applications. WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM[1]. WT-161 also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) [2].
CAS Number
[1206731-57-8]
Target
Apoptosis; Beta-lactamase; HDAC; Reference Standards
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Cancer
Smiles
O=C(N/N=C/C1=CC=C(N(C2=CC=CC=C2)C3=CC=CC=C3)C=C1)CCCCCCC(NO)=O
Molecular Formula
C27H30N4O3
Molecular Weight
458.55
References & Citations
[1]Hideshima T, et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proc Natl Acad Sci U S A. 2016 Nov 15;113 (46) :13162-13167.|[2]Severin Lechner, et al. Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nat Chem Biol. 2022 Apr 28.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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M-WS180320-1-ACWatershedTM System: A Humidity Controlled Workstation For Protein Crystallography with an added Air Compressor System Includes: - Humidity Control Unit (M-WS180320-HCU) - Relative Humidity Range: 50% to greater than 90% RH (110 V) - Active user controls for water temperature, stream humidity & air flow rate - Features quick-connect tubing adapters to allow easy switching between workstations - Humidified Chamber Workstation (M-WS180320-24WCSES) - accepts drops on 18 or 22 mm cover slips or on standard microscope slides - crystals can be harvested and manipulated within the workstation using standard tools - drops easily observed from above using a stereo microscope. - Directed Nozzle Workstation (M-WS180320-DNWS) - can be used with crystals in multi-well crystallization plates to provide a humidified air flow directed at a well being examined - crystals can be harvested and manipulated using standard tools - features magnetic adapter to allow nozzle to be affixed to the control unit or microscope base - Water Tank (M-WS180320-WT) - High durability polymer water tank (floor or desktop positionable) - Capacity: 2.5 gallons / 10 liters' - Air Compressor Unit **Please Include [Add Country] Power Cord** [ERASE IF USA]
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A20432-1WT-161 1mg
A20432-5WT-161 5mg
A20432-2WT-161 2mg
A20432-10WT-161 10mg
A20432-50WT-161 50mg
A20432-25WT-161 25mg
A20432-100WT-161 100mg

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