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BA 1 (TFA)

CAT: 0804-HY-P1423A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1423A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].
UNSPSC
12352209
Target
Bombesin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ba-1-tfa.html
Purity
99.35
Solubility
H2O : 16.67 mg/mL (ultrasonic)
Smiles
CCCC[C@@H](C(N)=O)NC([C@@H](NC([C@@H](NC(CCNC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](CC1=CC=C(O)C=C1)N)=O)CCC(N)=O)=O)CC2=CNC3=C2C=CC=C3)=O)C)=O)=O)=O)CC4=CN=CN4)=O)CC5=CC=CC=C5)=O.O=C(O)C(F)(F)F
Molecular Formula
C59H77F3N14O13
Molecular Weight
1247.32
References & Citations
[1]Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

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