BA 1

• UNSPSC Description:

  BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].

• Target Antigen:

  Bombesin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ba-1.html

• Solubility:

  H2O

• Smiles:

  O=C(CCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](N)CC1=CC=C(O)C=C1)=O)CCC(N)=O)=O)CC2=CNC3=CC=CC=C23)=O)C)=O)C(C)C)=O)N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCC)=O)CC4=CC=CC=C4)=O)CC5=CNC=N5

• Molecular Weight:

  1133.30

• References & Citations:

  [1]Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  183241-31-8