Recombinant Mouse IL-1 alpha

CAT: 0436-6578Size: 5 µgDry Ice: NoHazardous: No
CAT#:0436-6578Size:5 µg
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AVAILABILITY: InStock
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Description
IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Mouse IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.
Synonyms
Mouse ; IL-1 alpha
Label
ICT
Type
Recombinant Protein
Source
Yeast
Sequence
SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS (156)
Assay Protocol
The rat CXCL9/MIG protein can be used in cell culture, as a CXCL9/MIG ELISA Standard, and as a Western Blot Control.
Form
Lyophilized
Shipping Conditions
Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping
Storage Temperature
-20°C
Notes
20% discount
Calculated Molecular Weight
18.0 kDa
Target Description
IL-1 alpha is a member of the interleukin-1 family of cytokines, which encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the Well characterized members of the IL-1 cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are Well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an ‘alarmin’ released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.

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