Recombinant Mouse IL-4

• Description :

  IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Mouse IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

• Synonyms :

  Mouse ; IL-4

• Label :

  ICT

• Type :

  Recombinant Protein

• Source :

  Yeast

• Sequence :

  HIHGCDKNHL REIIGILNEV TGEGTPCTEM DVPNVLTATK NTTESELVCR ASKVLRIFYL KHGKTPCLKK NSSVLMELQR LFRAFRCLDS SISCTMNESK STSLKDFLES LKSIMQMDYS (120)

• Assay Protocol :

  The Mouse TNFSF11/RANKL protein can be used in cell culture, as an TNFSF11/RANKL ELISA Standard, and as a Western Blot Control.

• Form :

  Lyophilized

• Shipping Conditions :

  Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping

• Storage Temperature :

  -20°C

• Notes :

  20% discount

• Calculated Molecular Weight :

  13.6 kDa

• Target Description :

  Interkeukin-4 (IL-4) induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.