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Recombinant Cynomolgus TPBG/5T4 (C-6His)

CAT:
763-PKSQ050103-02
Size:
10 µg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Recombinant Cynomolgus TPBG/5T4 (C-6His) - image 1
Recombinant Cynomolgus TPBG/5T4 (C-6His) - image 2
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Recombinant Cynomolgus TPBG/5T4 (C-6His)

  • Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
  • Abbreviation: TPBG;5T4
  • Synonyms: 5T4 Protein, 5T4AG Protein, Human, M6P1 Protein, WAIF1 Protein
  • CAS Number: 9000-83-3
  • UniProt: Q4R8Y9
  • Accession Number: Q4R8Y9
  • Host: HEK293 Cells
  • Origin Species: Cynomolgus macaques
  • Tag: C-His
  • Sequence: Thr35-Ser355
  • Purity: > 95 % as determined by reducing SDS-PAGE.
  • Bioactivity: Not validated for activity
  • Reconstitution: Please refer to the printed manual for detailed information.
  • Molecular Weight: 55-80 kDa
  • Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
  • Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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