Recombinant Human TPBG/5T4 (C-Avi-6His) Biotinylated
CAT:
763-PKSH033889-02
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human TPBG/5T4 (C-Avi-6His) Biotinylated
- Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
- Abbreviation: TPBG;5T4
- Synonyms: 5T4, 5T4AG, M6P1, TPBG, WAIF1
- CAS Number: 9000-83-3
- UniProt: Q13641
- Accession Number: Q13641
- Host: HEK293 Cells
- Origin Species: Human
- Conjugation: Biotinylated
- Tag: C-Avi-His
- Sequence: Ser32-Ser355
- Field of Research: Cancer;Developmental Biology;immunology;Stem cells
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 50-90 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.