RIP3 Polyclonal Antibody

• Background:

  The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

• Abbreviation:

  RIP3

• UniProt:

  Q9Y572

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant fusion protein of human RIP3 (NP_006862.2) .

• Target:

  RIPK3; RIP3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC; IF

• Field of Research:

  Cancer; Cell Biology; Immunology; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  IHC 1:50-1:200; IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S2666027X22000093

• Isotype:

  IgG