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ST14 Polyclonal Antibody

CAT: 0763-D-AB-10208L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10208L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors.
Abbreviation
ST14
UniProt
Q9Y5Y6
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
Recombinant Human ST14 protein expressed by E.coli
Target
Epithin; HAI; Matriptase; Membrane type serine protease 1; Membrane type serine protease; Membrane-type serine protease 1; MT SP1; MT-SP1; MTSP 1; MTSP1; Prostamin; PRSS 14; PRSS14; Serine protease 14; Serine protease TADG 15; Serine protease TADG-15; Serine protease TADG15; SNC 19; SNC19; ST 14; ST14; ST14; Suppression of tumorigenicity 14 (colon carcinoma matriptase epithin) ; Suppression of tumorigenicity 14 (colon carcinoma) ; Suppression of tumorigenicity 14; Suppressor of tumorigenicity 14 protein; Suppressor of tumorigenicity protein 14; TADG 15; TADG15; TMPRSS14; Tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer; Cell Biology
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
95kDa
Observed Molecular Weight
95-105kDa
Isotype
IgG

UniProtKB · Q9Y5Y6

Suppressor of tumorigenicity 14 protein

ST14_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y5Y6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ST14
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.109
Processing
—
Secondary accessions
Q9BS01, Q9H3S0, Q9HB36, Q9HCA3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variantHypotrichosisIchthyosis

PTM

Disulfide bondGlycoprotein

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Membrane

Domain

RepeatSignal-anchorTransmembraneTransmembrane helix
Product Datasheet
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