POMC Polyclonal Antibody

• Background:

  Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH, α- and β-MSH, β-and γ-LPH, CLIP, β-endorphin, and N-POMC. POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety. POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat.

• Abbreviation:

  POMC

• UniProt:

  P01189

• Host:

  Rabbit

• Reactivity:

  Mouse; Rat

• Immunogen:

  Synthetic peptide.

• Target:

  Pro-opiomelanocortin; Corticotropin-lipotropin; NPP; Melanotropin gamma; Gamma-MSH; Potential peptide; Corticotropin; ACTH; CLIP; Alpha-MSH; Beta-LPH; Gamma-LPH; Beta-MSH; Beta-endorphin; Met-enkephalin

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Metabolism; Neuroscience; Signal Transduction

• Purification:

  Antigen Affinity Purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-1:2000

• Buffer:

  PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  29 kDa

• Observed Molecular Weight:

  35 kDa, 16 kDa

• Isotype:

  IgG