POMC Polyclonal Antibody

• Background :

  Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH, α- and β-MSH, β-and γ-LPH, CLIP, β-endorphin, and N-POMC. POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety. POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat.

• Abbreviation :

  POMC

• UniProt :

  P01189

• Host :

  Rabbit

• Reactivity :

  Mouse; Rat

• Immunogen :

  Synthetic peptide.

• Target :

  Pro-opiomelanocortin; Corticotropin-lipotropin; NPP; Melanotropin gamma; Gamma-MSH; Potential peptide; Corticotropin; ACTH; CLIP; Alpha-MSH; Beta-LPH; Gamma-LPH; Beta-MSH; Beta-endorphin; Met-enkephalin

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Metabolism; Neuroscience; Signal Transduction

• Purification :

  Antigen Affinity Purification

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:1000-1:2000

• Buffer :

  PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  29 kDa

• Observed Molecular Weight :

  35 kDa, 16 kDa

• Isotype :

  IgG