MITF Polyclonal Antibody

• Background :

  This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Abbreviation :

  MITF

• UniProt :

  O75030

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Recombinant fusion protein of human MITF (NP_937801.1) .

• Target :

  MITF; CMM8; COMMAD; MI; WS2; WS2A; bHLHe32

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Epigenetics and Nuclear Signaling; Immunology

• Purification :

  Affinity purification

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  40kDa/46kDa/52kDa/55kDa/56kDa/57kDa/58kDa

• Observed Molecular Weight :

  65kDa

• Citation 01 :

  https://www.sciencedirect.com/science/article/pii/S0923181120302000

• Isotype :

  IgG