AURKAIP1 Polyclonal Antibody

AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

AURKAIP1

Q9NWT8

Human

Recombinant protein of human AURKAIP1

28S ribosomal protein S38; AIP; AKIP; AURKA interacting protein; AURKA-interacting protein; AURKAIP 1; Aurkaip1; Aurora A kinase interacting protein; Aurora kinase A interacting protein 1; Aurora kinase A-interacting protein; FLJ20608; mitochondrial; MRP-S38

Unconjugated

WB

Cancer; Cell Biology

Affinity purification

0.2 mg/mL

WB 1:500-1:2000

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

22kDa