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PDE1-IN-2

CAT: 0804-HY-101490-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-101490-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDE1-IN-2 is a PDE1 inhibitor extracted from patent WO2016/55618 A1, example 31. PDE1-IN-2 has IC50 values of 6 nM, 140 nM and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. PDE1-IN-2 is developed for the research of neurodegenerative disorders and psychiatric disorders[1].
CAS Number
1904611-63-7
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/PDE1-IN-2.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=NN=C(C3CCOCC3)N2C=C(Br)N1CC4CCCC4
Molecular Formula
C16H21BrN4O2
Molecular Weight
381.27
References & Citations
[1]Jan Kehler, et al. Triazolopyrazinones as pde1 inhibitors. WO2016055618A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE1

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