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Methyldopate

CAT: 0804-HY-B1696-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1696-01Size:5 mg
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Description
Methyldopate is an ethyl ester proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L- (-) -α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate has the potential for severe hypertension research.
CAS Number
6014-30-8
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/methyldopate.html
Purity
98.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC([C@@](C)(N)CC1=CC(O)=C(C=C1)O)=O
Molecular Formula
C12H17NO4
Molecular Weight
239.27
Precautions
H302, H312, H332
References & Citations
[1]Hoskins JA, et al. Determination of alpha-methyldopa and methyldopate in human breast milk and plasma by ion-exchange chromatography using electrochemical detection. J Chromatogr. 1982 Jun 11;230 (1) :162-7. |[2]P D Walson, et al. Metabolic disposition and cardiovascular effects of methyldopate in unanesthetized rhesus monkeys. J Pharmacol Exp Ther. 1975 Oct;195 (1) :151-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor