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Methyldopa (hydrochloride)

CAT: 0804-HY-B0225ASize: 1 EachDry Ice: NoHazardous: No
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Description
Methyldopa hydrochloride (L- (-) -α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) . Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].
CAS Number
884-39-9
Product Name Alternative
L- (-) -α-Methyldopa (hydrochloride) ; MK-351 (hydrochloride)
UNSPSC
12352005
Target
Adrenergic Receptor; Endogenous Metabolite
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/l-_-_-_alpha_-methyldopa-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1.Cl
Molecular Formula
C10H14ClNO4
Molecular Weight
247.68
References & Citations
[1]Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6 (5 Pt 2) :II51-II56.|[2]Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78 (3) :342-350.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

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