Methyldopa (hydrate) (Standard)

• UNSPSC Description:

  Methyldopa (hydrate) (Standard) is the analytical standard of Methyldopa (hydrate). This product is intended for research and analytical applications. Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].

• Target Antigen:

  Adrenergic Receptor; Endogenous Metabolite

• Type:

  Reference Standards

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

• Field of Research:

  Cardiovascular Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/methyldopa-hydrate-standard.html

• Smiles:

  OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1.O

• Molecular Weight:

  238.24

• References & Citations:

  [1]Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56.|[2]Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78(3):342-350.

• Shipping Conditions:

  Room temperature

• CAS Number:

  41372-08-1