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β-Naphthoflavone-CH2-Br

CAT: 0804-HY-130842-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130842-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1.
CAS Number
1282513-77-2
Product Name Alternative
β-NF-CH2-Br
UNSPSC
12352005
Hazard Statement
H302-H314
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/β-naphthoflavone-ch2-br.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=C(CBr)C=C2)OC3=C1C4=CC=CC=C4C=C3
Molecular Formula
C20H13BrO2
Molecular Weight
365.22
Precautions
P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
References & Citations
[1]Ohoka N, et al. Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS Chem Biol. 2019 Oct 16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IAP

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