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β-Naphthoflavone (Standard)

CAT: 0804-HY-114740R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114740R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Naphthoflavone (Standard) is the analytical standard of β-Naphthoflavone. This product is intended for research and analytical applications. β-Naphthoflavone is an exogenous aryl hydrocarbon receptor (AHR) ligand. β-Naphthoflavone can activate AHR to participate in various biological processes, including cell growth, differentiation, apoptosis, and metabolism. β-Naphthoflavone has antioxidant activity and can exert its antioxidant function by regulating the activity of antioxidant enzymes. β-Naphthoflavone is also a non-carcinogenic CYP1A inducer and can be used to treat aristolochic acid (AAI) induced renal injury[1][2][3].
CAS Number
6051-87-2
UNSPSC
12352100
Target
Apoptosis; Aryl Hydrocarbon Receptor; Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; Others
Field of Research
Cancer; Neurological Disease
Smiles
O=C1C2=C3C=CC=CC3=CC=C2OC(C4=CC=CC=C4)=C1
Molecular Formula
C19H12O2
Molecular Weight
272.30
References & Citations
[1]Ishida T, Takechi S. β-Naphthoflavone, an exogenous ligand of aryl hydrocarbon receptor, disrupts zinc homeostasis in human hepatoma HepG2 cells. J Toxicol Sci. 2019;44 (10) :711-720.|[2]Zhu Y, et al. α- and β-Naphthoflavone synergistically attenuate H2O2-induced neuron SH-SY5Y cell damage. Exp Ther Med. 2017 Mar;13 (3) :1143-1150. |[3]Ying Xiao, et al. β-Naphthoflavone protects mice from aristolochic acid-I-induced acute kidney injury in a CYP1A dependent mechanism. Acta Pharmacologica Sinica 30.11 (2009) : 1559-1565.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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