Thalidomide-NH-CH2-CONH-C6-Br

• UNSPSC Description:

  Thalidomide-NH-CH2-CONH-C6-Br is an E3 ligase ligand-linker conjugate that can be used to synthesize DD-03-171 (HY-122830)[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-nh-ch2-conh-c6-br.html

• Smiles:

  O=C(NCCCCCCBr)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

• Molecular Weight:

  493.35

• References & Citations:

  [1]Dennis Dobrovolsky, et al. Bruton’s Tyrosine Kinase Degradation as a Therapeutic Strategy for Cancer. Blood. 2019 Feb 28;133(9):952-961.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported