GPR61 Inverse agonist 1

• UNSPSC Description:

  GPR61 Inverse agonist 1 (Compound 1) is a GPR61 inverse agonist (IC50: 11 nM). GPR61 Inverse agonist 1 can be used for research of disorders of metabolism and body weight, such as obesity and cachexia[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gpr61-inverse-agonist-1.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  FC1=C(C(F)=CN=C1)CNC2=NC(OC)=C(C=C2)S(N(C3=NC(OCC)=CC(C)=N3)CCOC)(=O)=O

• Molecular Weight:

  524.54

• References & Citations:

  [1]Lees JA, et al. An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism. Nat Commun. 2023 Sep 23;14(1):5938.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported