CB1 inverse agonist 2

• UNSPSC Description:

  CB1 inverse agonist 2 is an orally active inverse agonist of Cannabinoid Receptor CB1. CB1 inverse agonist 2 effectively inhibits CP55940-induced hypothermia and anorexia in mice model[1].

• Target Antigen:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cb1-inverse-agonist-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C2SC3=CC=CC=C3C(C4=CC=C(F)C(Cl)=C4)=NC2=C1)NCCCC

• Molecular Weight:

  438.94

• References & Citations:

  [1]Synthesis and Evaluation of Dibenzothiazepines: A Novel Class of Selective Cannabinoid-1 Receptor Inverse Agonists J. Med. Chem., 2009, 52 (7), pp 1975-1982|[2]Pettersson H, et al. Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists. J Med Chem. 2009 Apr 9;52(7):1975-82.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1019839-52-1