Antitrypanosomal agent 1
CAT:
804-HY-W052512-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Antitrypanosomal agent 1
- CAS Number: 9007-83-4
- UNSPSC Description: Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity[1].
- Target Antigen: Parasite
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/antitrypanosomal-agent-1.html
- Purity: 95.0
- Solubility: DMSO : 25 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=C(Cl)C(Cl)=C1)CCN(C)C.[H]Cl
- Molecular Weight: 282.598
- References & Citations: [1]Martyn DC, et al. High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1280-3.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported