Antitrypanosomal agent 7

• Target :

  Others|||Parasite

• Related Pathways :

  Microbiology/Virology|||Others

• Bioactivity :

  The Antitrypanosomal agent 7 (compound 18c) is a potent anti-trypanosome agent and shows good ADME properties. The Antitrypanosomal agent 7 was more than two-fold more active against T. brucei (IC50: 0.71 ?M) than Nifurtimox. Antitrypanosomal agent 7 has a strong interaction with DNA and can selectively bind to AT-rich DNA.

• Smiles :

  O(C)C=1C=C(C=2NC=3C(N2)=CC=C(C3)C=4NCCN4)C=CC1OCCN(CC)CC

• Molecular Formula :

  C23H29N5O2

• Molecular Weight :

  407.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2492436-38-9