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Antitrypanosomal agent 7

CAT: 0931-T63167-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63167-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2492436-38-9
Target
Others, Parasite
Related Pathways
Microbiology/Virology, Others
Bioactivity
The Antitrypanosomal agent 7 (compound 18c) is a potent anti-trypanosome agent and shows good ADME properties. The Antitrypanosomal agent 7 was more than two-fold more active against T. brucei (IC50: 0.71 μM) than Nifurtimox. Antitrypanosomal agent 7 has a strong interaction with DNA and can selectively bind to AT-rich DNA.
Smiles
O(C)C=1C=C(C=2NC=3C(N2)=CC=C(C3)C=4NCCN4)C=CC1OCCN(CC)CC
Molecular Formula
C23H29N5O2
Molecular Weight
407.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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